Novel roles for mTORC1-dependent translational control during synaptic homeostasis
نویسندگان
چکیده
منابع مشابه
Retrograde changes in presynaptic function driven by dendritic mTORC1.
Mutations that alter signaling through the mammalian target of rapamycin complex 1 (mTORC1), a well established regulator of neuronal protein synthesis, have been linked to autism and cognitive dysfunction. Although previous studies have established a role for mTORC1 as necessary for enduring changes in postsynaptic function, here we demonstrate that dendritic mTORC1 activation in rat hippocamp...
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